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Cell fate
DC development, lineage specification & epigenetic control
We map enhancers, chromatin accessibility and transcription factor networks to understand how DC subsets emerge from progenitors and acquire specialized functions.
Institute of Experimental Immunology · UZH
Deciphering dendritic cell development, identity and function.
We investigate how dendritic cell subsets develop, acquire specialized functions, and shape immune responses in health and disease.
Research
From progenitors to specialized immune functions.
Three main topics, united by one question: how do transcriptional and epigenetic programs determine what a dendritic cell becomes and what it does?
Mucosal immunity
RORγt⁺ dendritic cells & tolerance
We study RORγt⁺ DCs in food tolerance, peripheral Treg induction, intestinal homeostasis and the regulation of type 2 immunity.
Immune diversity
pDCs and pDC-like derived cDC2
We investigate plasmacytoid DCs, pDC-like cells, cDC2 heterogeneity, and their roles in antiviral immunity, autoimmunity and cancer.
People
A growing team working on DC immunology.
- Research position
- Group Leader
- Research interests
- Dendritic cell development, immune tolerance, transcriptional and epigenetic control
- Nationality
- Portuguese
- Position
- Administrative Assistant
- Email Carmen
- Telephone
- +41 44 635 37 02
- Research position
- PhD Student
- Research interests
- Dendritic cell development, epigenetic and transcriptional regulation of DC subsets
- Nationality
- Italian
- Joined the lab
- 2 November 2026
- Research position
- PhD Student
- Research interests
- Functional aspects of dendritic cell heterogeneity
- Nationality
- Swiss
- Joined the lab
- 2 November 2026
Master Student
Open position
Master Student
Open position
The Rodrigues Lab is a team where everyone contributes equally to science. Our research focuses on dendritic cell development, immune tolerance, and the transcriptional and epigenetic mechanisms that control immune cell specialization.
Publications
Selected work.
Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells.
Nature ImmunologyPubMed Central 
DOI
News
Latest from the lab.
Welcome Enrico and Luana to the Rodrigues Lab.
Enrico Testori and Luana Piano Vieira join the lab as PhD students, bringing new perspectives to dendritic cell development, regulation and heterogeneity.
Meet the team ↗We are recruiting motivated team members.
Postdocs, PhD students, technicians and Master/Bachelor students with a passion for immunology and genomics are encouraged to get in touch.
Read more ↗New research directions in dendritic cell biology and immune tolerance.
From RORγt⁺ DCs to pDC-like cells: an overview of the questions and tools shaping the lab's first years.
Read more ↗Contact
Get in touch.
Interested in a position, a collaboration, or simply a chat about dendritic cells? We’d love to hear from you.
Contact the lab
For positions, collaborations and scientific enquiries.
Institute of Experimental ImmunologyUniversity of Zurich
Winterthurerstrasse 1908057 Zürich, Switzerland